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KMID : 1103720100630060537
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Journal of the Korean Society of Radiology
2010 Volume.63 No. 6 p.537 ~ p.546
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Hepatic Angiomyolipoma: Dual-Contrast MRI Findings Using Superparamagnetic Iron Oxide (SPIO) and Gadolinium Agents
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Kim Min-Uk
Choi Byung-Ihn
Kim Se-Hyung
Kim Hyo-Cheol
Lee Jae-Young
Kim Min-A
Han Joon-Koo
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Abstract
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Purpose: To analyze imaging findings of hepatic angiomyolipomas (AMLs) on dualcontrast MRI using superparamagnetic iron oxide (SPIO) and gadolinium (Gd) agents.
Materials and Methods : Five histopathologically-proven hepatic AMLs were enrolled in this study. Patients underwent dual-contrast MRI using SPIO and Gd agents on a 3.0T unit and performed a qualitative analysis consisting of measuring the signal intensity (SI) of the lesion, presence of fat, hemorrhage, early draining vein, tortuous tumoral vessels, as well as capsule and enhancement patterns. The signal drop of the lesion on post-SPIO images was also assessed. For the quantitative analysis, relative signal decrease (RSD, %) was calculated.
Results: The presence of fat was noted in three lesions. An early draining vein and prominent tortous tumoral vessels were depicted in four lesions. No lesion was found to have a capsule. Four lesions showed early wash-in and early wash-out enhancement patterns, while the remaining lesion depicted strong and persistent enhancement. On post-SPIO images, signal drop was noted in the two lesions with no fat within the lesion. Their RSD was 21.1% and 38.0%, respectively.
Conclusion:The presence of an early draining vein and tortuous tumoral vessels are characteristic dynamic enhanced MRI features of hepatic AMLs. In fat-deficient hepatic AMLs, the combination of dynamic enhanced MRI and SPIO-enhanced MRI might findings might increase the accuracy of making a correct diagnosis.
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KEYWORD
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Angiomyolipoma, Liver, Dual contrast Magnetic Resonance Imaging, Superparamagnetic Iron Oxide
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